Tools for analysis of 23andme genetic info

What do your genes say about you!?

You can find out by running the 23andme test.* And once you do, there are so many tools to help you analyze your genetic info and make the most of your results. *Full disclosure: that link includes a referral code that gives me a tiny kickback.

With my clients, I focus on the genetic info that describes your body’s ability to methylate (MTHFR) and detoxify. But there are so many other relevant topics, such as locating relatives/ancestors for family trees, mapping your genome, locating all the research on a particular gene and more.

Here are three tools to start with. They’ll provide general info, specific nutrition/supplementation insight and athletic profiling:

Please remember: Genetic info is not the be all end all when it comes to disease risk… the study of Epigenetics (as well as common sense) proves that your environment** acts upon your genetics and ultimately has the greatest impact on your health. You can feel empowered by that! **Environment = air, food, microbes, relationships, emotions and more.

1. PureGenomics offers an analysis of a few key genes that affect methylation,  detox, mental health & cognition, weight management and nutrient metabolism.
   • Unfortunately, they don’t just give this info away– It is free, but someone deemed to be a “practitioner” needs to set up an account for you. I will happily get you access for a small fee to cover my time (fee = whatever you choose to give).  Please see below for how to get this done.
   • The site will provide you with 2 resources (please scroll to the bottom of this post for images of some samples): “Personalized Table,” which lists Pure Encapsulations supplements that might benefit you, and “Personalized Graph,” which indicate which part of various pathways may be affected by your unique genetic makeup. Find these at the top, under “My Results.”
   • The site also provides a list of which PureEncapsulations products their research deems best for each of your SNPs. Unfortunately, you can’t generate this report– it can only be done by the practitioner who created your account.
   • Here’s what to do if you would like me create a PureGenomics account for you:
     1. Send me a few crumbs (say 5 bucks?… whatever works for you) via PayPal or Venmo. Please mention PureGenomics and include your email address.
     2. I’ll create your account as soon as I can & email a confirmation.
     3. You’ll get an email from PureGenomics with instructions. You can either upload your 23andme data by providing your login info or uploading the raw data directly. (*To access your 23andme raw data, find instructions here.)
     4. Once you upload your 23andme data, I’ll be notified by the PureGenomics site. At that point, I’ll generate your supplement report and email it to you. I can only do this if you allow me to view your results. Please see disclaimer below.
     5. **Implicit in your request for the PureGenomics supplement recommendations is an understanding that I’ll be able to see your data. (If you allow it, I will only have access to the info produced by PureGenomics, which is a mere subset of your 23andme data). I won’t look at your data. I’ll download the analysis, email it to you and then delete both the file and the email. I care a whole heck of a lot about your privacy! After you get my email, feel free to hide your data from me by going to Account –> My Account, then unchecking the box at the very top, next to “Allow my practitioner, Anne Buzzelli to view my results.”
   • If you want to order any of the products from the recommendation, I’m happy to be able to help you get a 15% discount at my online dispensaries! (Transparency alert: I get a small kickback on purchases, so it’s a win-win… Plus, unfortunately, you can trust these sites, unlike the discounted vendors on Amazon and eBay.)
2. Athletigen provides insight about your ideal forms of exercise. This includes things like endurance, muscle type and recovery time. *Please see the comment from Athletigen below for updated information.*

If you want to dig a little deeper, check these out:

• **To access your 23andme raw data, find instructions here.
• GeneticGenie provides you with both a Methylation Analysis and a Detox Profile. The former will indicate whether you need to tweak your diet and supplementation (especially to make sure you’re taking the correct forms of folate and B12). The latter will help you understand how well your body can detoxify (this output is much less helpful than the methylation analysis).
• Promethease creates a report for $5. It’s a mess of data, but I don’t recommend it unless you’re planning to dig deep.
• Livewello offers a comprehensive look at the relationship between your genetics and physical traits & disease risk (all for $19.95).
• CodeGen.eu offers “tools to help you explore your individual 1600-3000 page report: modern search, over 2000 topics, major categories, filters, favorites, social genomics.” Includes “Psychological traits such as resilience, stress response, empathy, etc.”
• NutraHacker has some free features: “After a short 29 question anonymous survey that contributes to research, receive a FREE detoxification and methylation analysis (examining 49 SNPs) that will help clarify your nutritional needs. You also receive a FREE placebo tendency analysis report.” Full report is $23 and includes all future updates.
• Infino.me offers a good cause & some great visuals. It is “a citizen science experiment to help people lose weight, feel better, and live longer. By bringing together the right data we can understand the interactions between genetics and lifestyle for the good of science! Our tools give you an overview of the genetic risk profile of several diseases, and match you with open-access literature written about specific genetic variants.”
• Enlis.com offers a free genome report, but to download it you have to hand over $40.
• GeneKnot.com allows you to “find users with similar DNA and share the experience.”

Even MORE tools can be found at these links:

• TheGeneticGenealogist.com
• 23andyou: 3rd Party Tools
• 23andyou: Features found inside 23andme
• Some ancestry-specific tools here: http://www.23andyou.com/3rdparty
• Are you an awesome nerd who wants to map your chromosomes? Well, here’s some info… please explain it to me! http://www.isogg.org/wiki/Chromosome_mapping

If you find anything cool (like a long-lost relative living down the hall in your apartment building) or another tool (that identifies alien DNA or designs specific fashion that best suits your genes), please let me know pronto!

 

---

The following are sample reports from the PureGenomics analysis mentioned above:

Personalized Report (this is just a snippet):

Personalized Diagrams (2 of many):

 

 

 

 

 

Supplement report